Is Spero Therapeutics, Inc. SPRO stock Halal to invest in?

No, as of September 2026, Spero Therapeutics, Inc. stock (SPRO) is not currently classified as a Shariah compliant stock. This verdict follows the screening methodology of AAOIFI (the Accounting and Auditing Organization for Islamic Financial Institutions), whose Shariah Standard No. 21 is the leading global benchmark for screening Halal stocks. To qualify as Halal under this standard, a company must keep non-permissible income below 5% of total revenue, keep both interest-bearing investments and interest-bearing debt below 30% of market capitalisation, and have no impermissible preference share structure. Spero Therapeutics, Inc. currently does not meet the threshold for the non-permissible income and interest-bearing investments screens. Because screenings are refreshed monthly as new financial reports are published, a non-compliant stock can regain compliant status if its financial structure changes. You can track the latest status of Spero Therapeutics, Inc. and discover Shariah compliant alternatives among the Halal stocks in the Tabadulat app.

How often is Spero Therapeutics, Inc. SPRO reviewed for Shariah compliance?

Tabadulat reviews Spero Therapeutics, Inc. SPRO for Shariah compliance every month. Each review applies the AAOIFI Shariah Standard No. 21 methodology, screening the company's business activities, non-permissible income, interest-bearing investments, interest-bearing debt, and preference shares, against the company's latest available financial data. The process operates under the direct supervision of Tabadulat's dedicated Shariah Supervisory Board of Islamic finance scholars. Because compliance depends on financial ratios that move with market capitalisation and reported results, a stock's status can change from one review to the next. Monthly screening ensures the status shown for Spero Therapeutics, Inc. reflects current financial data rather than an outdated assessment, and Tabadulat app users are notified if a holding in their portfolio becomes non-compliant.

Does Spero Therapeutics, Inc. SPRO pass the AAOIFI Non Permissible Income criteria?

No, as of September 2026, Spero Therapeutics, Inc. stock (SPRO) does not pass the AAOIFI non-permissible income screen. Under AAOIFI Shariah Standard No. 21, income from impermissible sources (such as interest or Riba, conventional financial services, alcohol, gambling, or tobacco) must remain below 5% of a company's total revenue. Spero Therapeutics, Inc.'s income from non-permissible sources currently exceeds this 5% ceiling, which makes the stock non-compliant on this criterion regardless of how it performs on the other screens. The screen is reassessed monthly, so the status can change when the company releases new financial statements.

Does Spero Therapeutics, Inc. SPRO pass the AAOIFI Interest Bearing Investments criteria?

No, as of September 2026, Spero Therapeutics, Inc. stock (SPRO) does not pass the AAOIFI interest-bearing investments screen. Under AAOIFI Shariah Standard No. 21, the cash a company places in interest-earning instruments (such as conventional deposits, bonds, treasury bills and money-market funds) must remain below 30% of its market capitalisation. Spero Therapeutics, Inc.'s interest-bearing investments currently exceed this 30% limit, meaning too large a share of the company's value derives from Riba-based instruments for the stock to qualify as Halal on this criterion. The ratio moves with both the balance sheet and the share price, and is reassessed monthly.

Does Spero Therapeutics, Inc. SPRO pass the AAOIFI Interest Bearing Debt criteria?

Yes, as of September 2026, Spero Therapeutics, Inc. stock (SPRO) passes the AAOIFI interest-bearing debt screen. Each month Tabadulat measures Spero Therapeutics, Inc.'s interest-accruing borrowings against AAOIFI's 30% market capitalisation cap. The current screening shows the company within the limit, so the debt screen passes. Because market capitalisation changes daily, a company's debt ratio can drift toward or away from the limit even without new borrowing, which is why this screen is reassessed every month.

What is the dividend purification factor for Spero Therapeutics, Inc. SPRO stock?

Spero Therapeutics, Inc. (SPRO) is currently classified as not Shariah compliant, so no dividend purification factor applies, because purification factors are calculated only for stocks that pass the AAOIFI screens. Purification (Tazkiyah) is the practice of donating to charity the small portion of dividend income that stems from incidental non-permissible sources, such as interest earned on a compliant company's cash deposits. For non-compliant stocks the issue is not purification but eligibility: under AAOIFI Shariah Standard No. 21 the stock does not currently qualify as a Halal investment. If Spero Therapeutics, Inc. returns to compliance in a future monthly screening, its purification factor will be published alongside its updated status in the Tabadulat app.

Does Spero Therapeutics, Inc. SPRO pass the AAOIFI Preference Share screen?

Yes, as of September 2026, Spero Therapeutics, Inc. stock (SPRO) passes the AAOIFI preference share screen. AAOIFI Shariah Standard No. 21 prohibits investing in preference shares because they grant holders guaranteed or priority rights to dividends and capital ahead of ordinary shareholders, a structure that conflicts with the Shariah principle that investors should share profit and loss in proportion to their ownership. Spero Therapeutics, Inc. has no impermissible preference share structure affecting its ordinary shares, so the stock is compliant on this criterion. Like all AAOIFI screens, this is verified in each monthly review.

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Is Spero Therapeutics (SPRO) stock Halal?

NASDAQ

Shariah-Compliant

Not Shariah

As of the September 2026 screening, Spero Therapeutics, Inc. (SPRO) does not meet the AAOIFI Shariah Standard No. 21 threshold for the non-permissible income and interest-bearing investments screens, so the stock is not currently classified as Shariah compliant. It is re-screened every month and can regain compliance if its financial structure changes.

Sector:

Healthcare

Industry:

Biotechnology

Employees:

Website:

https://sperotherapeutics.com

Market cap:

$71M

P/E ratio:

8.6

Dividend yield:

52-week range:

$1.08 - $3.08

Data as of:

3 September 2026

Screening history:

September 2026: FAIL

Spero Therapeutics is a biopharmaceutical company focused on developing novel treatments for infectious diseases, particularly those caused by antibiotic-resistant bacteria. The primary function of Spero Therapeutics is to address the growing global challenge of bacterial infections that are difficult to treat with existing antibiotics. The company’s pipeline includes innovative therapies targeted at multi-drug resistant bacterial infections, which are essential in hospital and healthcare environments. For Muslim investors, though, the most pressing question is simpler: is Spero Therapeutics a Halal investment?

Is Spero Therapeutics Shariah compliant?

Technology companies rarely fail AAOIFI screening on what they sell. Software, hardware and digital services are permissible business activities, so for a company like Spero Therapeutics the Shariah question moves to the balance sheet: how much of its market value sits in interest bearing debt, how much of its cash earns Riba in conventional deposits, and whether incidental income from impermissible sources creeps past 5% of revenue. These are exactly the ratios AAOIFI Shariah Standard No. 21 polices, and they move every month with the share price.

Does Spero Therapeutics pass the business activity test?

The activity screen is only part of the picture this month: Spero Therapeutics currently fails the non-permissible income and interest-bearing investments screens, so the overall verdict is not compliant regardless of the business itself. The watch item for technology names is incidental: cash returns and platform content can carry impermissible elements, which AAOIFI tolerates only below the thresholds.

Is Spero Therapeutics' income Halal?

No. Spero Therapeutics' income from impermissible sources currently exceeds AAOIFI's 5% revenue ceiling, which makes the stock non-compliant on this screen regardless of the others. The screen is reassessed monthly, so the status can change when new financial statements arrive.

Does Spero Therapeutics meet AAOIFI's debt and investment ratio requirements?

Not in full. Interest bearing investments currently exceed the 30% cap, while the other ratio stays within it. One breach is enough to fail the screening; the ratios are reassessed monthly under our Shariah Supervisory Board.

Tabadulat is an ADGM regulated brokerage whose license covers Shari'a Compliant Regulated Activities, as the FSRA permission names them. New to the terminology? Gharar and Maysir, Sukuk, Zakat and purification are all explained in plain English.

New to the four screens? Read Why a Halal Stock Screener Matters for Halal Investing

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